The main thing to remember is that cannabis oil is made for ingestion rather than inhalation. Despite the fact that some cannabis extracts made for smoking/vapourizing can contain more than 50% THC by weight (versus 2-3% THC in our cannabis oils), the amount (grams or millilitres) of cannabis oil used by patients is much greater than their inhaled counterparts. Therefore a typical dose of THC (in mg) is quite comparable.

Neural regeneration: Although chronic stress can damage neurons and even shrink brains, certain areas of the brain are still capable of regeneration. Throughout our lives we continue to form new neurons, make new connections, and grow our brains — and CBD apparently boosts this process. This means that CBD could help to counterbalance the brain damage caused by chronic stress. Numerous studies have proved that CBD encourages neural regeneration, particularly in the hippocampus. In fact, its ability to reduce anxiety in chronically-stressed mice comes from CBD’s power to stimulate the growth of new neurons. (For more on CBD’s role in neuroplasticity and neural regeneration, see our upcoming article on depression.)


Cannabidiol (CBD) is a naturally-occurring constituent of industrial hemp (cannabis sativa) plants. It is the most abundant non-psychoactive cannabinoid found in cannabis and is being scientifically investigated for numerous reasons. Most people have heard of a cannabinoid called THC, which is the ingredient in cannabis that gets users high. Unlike THC, CBD (cannabidiol) is a non-psychoactive cannabinoid and does not cause a high.
In fact, the U.S. Food and Drug Administration (FDA) approved Epidiolex (a drug made with a purified form of CBD oil) in June 2018 for the treatment of seizures associated with two rare and severe forms of epilepsy in patients 2 years of age and older. These two epilepsy forms are known as Lennox-Gastaut syndrome and Dravet syndrome. Epidiolex is the first FDA-approved drug that contains a purified drug substance derived from marijuana.
“THC”—the more-famous, high-inducing compound in cannabis—“works directly on the cannabinoid system, meaning it attaches to receptors and mimics some of our own internal endocannabinoids,” says Igor Grant, a professor and chair of psychiatry at the University of California, San Diego School of Medicine. But CBD’s interaction with the endocannabinoid system is subtler. “Normally, these endocannabinoid-signaling molecules are broken down by enzymes, and one thing CBD does is interfere with the actions of those enzymes.”
One of the most profound uses of cannabidiol oil is for the relief of arthritic pain. There are two kinds of arthritis, rheumatoid and osteoarthritis, both resulting in swelling and stiffness in joints.  Scientific studies have documented that the application of CBD oil can help assuage the pain caused by inflammations. Results have been encouraging. Health associations and the government, alike, are optimistic about the role of CBD oil in bringing solace to arthritic patients.

In 1937, the U.S. Treasury Department introduced the Marihuana Tax Act, which imposed a levy of $1 per ounce for medicinal use of cannabis and $100 per ounce for recreational use. This was opposed by physicians who were not required to pay a special tax for prescribing cannabis, use special order forms to obtain it and keep records detailing its professional use. The American Medical Association believed that evidence of cannabis’ harmful effects was limited and the act would prevent further research into its medicinal worth.


If you haven’t been bombarded with CBD marketing or raves about it from friends, get ready. This extract—which comes from either marijuana or its industrial cousin, hemp—is popping up everywhere. There are CBD capsules, tinctures, and liquids for vaping plus CBD-infused lotions, beauty products, snacks, coffee, and even vaginal suppositories. Already some 1,000 brands of CBD products are available in stores—and online in states that don’t have lenient cannabis laws. This is a tiny fraction of what’s to come: The CBD market is poised to exceed $1 billion by 2020, per the Chicago-based research firm Brightfield Group.
The ECS is responsible for setting the baseline activity levels of our immune system and nervous system, which then work to maintain our health. When the ECS falls out of whack, the systems that are regulated by it can begin to malfunction. CBD promotes the normal health and function of the endocannabinoid system, so it’s possible that CBD can help to alleviate the symptoms of conditions that are caused by dysfunction of the endocannabinoid system.

1 Active Not Recruiting Treatment Fumarate Hydratase (FH)-Deficient Tumors / Lung Cancer Non-Small Cell Cancer (NSCLC) / Mesothelioma / Renal Cell Adenocarcinoma / Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST) / Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal Stromal Tumors / Triple-Negative Breast Cancer (TNBC) / Tumors Harboring Amplifications in the cMyc Gene / Tumors Harboring Isocitrate Dehydrogenase-1 (IDH1) and IDH2 Mutations / Tumors, Solid 1
Yet even those who believe in this power recognize that CBD medicine remains largely unexplored: Treatments are not systematized, many products are not standardized or tested, and patients (or their parents) are generally left to figure out dosing on their own. While some suppliers and dispensaries test the CBD and THC levels of their products, many do not. “We really need more research, and more evidence,” Kogan says. “This has to be done scientifically.”
These cannabinoid-rich extracts can pose risks to patients who consume them. The exact composition of different available oils is frequently unknown. They are not checked for quality by external certified laboratories for the presence of residual solvents, or contaminants such as microbes, pesticides, heavy metals or mycotoxins. The lack of standardisation of both the cannabis starting material and oils makes it impossible to fully evaluate their therapeutic effects over time and, hence, their medicinal value.
Cannatonic: A potent pain-reliever, Cannatonic hails from Spain and stands as one of the earliest cultivars to be bred for its high CBD content. This cultivar is a cross between MK Ultra and G13 Haze, and it helps relieves anxiety, muscle spasms, pain, and migraines while providing uplifting energy. Cannatonic tends to relax and loosen muscles without locking users to their couches.
Schizophrenia. Research on the use of cannabidiol for psychotic symptoms in people with schizophrenia is conflicting. Some early research suggests that taking cannabidiol four times daily for 4 weeks improves psychotic symptoms and might be as effective as the antipsychotic medication amisulpride. However, other early research suggests that taking cannabidiol for 14 days is not beneficial. The conflicting results might be related to the cannabidiol dose used and duration of treatment.
CBD hemp oil has been proven in clinical trials to benefit humans and animals alike, as we both have endocannabinoid systems and are receptive to the chemical compound. Current studies also show that it is impossible to overdose on the substance. There is no need to worry if your dog takes a larger dose of CBD than anticipated – it is highly unlikely to have any negative effects, making it a safe and easy alternative treatment for your pet.
CBD has also been shown to have neuroprotective properties in cell cultures as well as in animal models of several neurodegenerative diseases, including Alzheimer’s,xii,xiii,xiv stroke,xv glutamate toxicity,xvi multiple sclerosis (MS),xvii Parkinson’s disease,xviii and neurodegeneration caused by alcohol abuse.xix Nabiximols (trade name Sativex), which contains THC and CBD in roughly equal proportions, has been approved throughout most of Europe and in a number of other countries for the treatment of spasticity associated with MS. It has not been approved in the United States, but clinical trials are ongoing, and two recent studies reported that nabiximols reduced the severity of spasticity in MS patients.xx,xxi There have been limited clinical trials to assess the potential efficacy of CBD for the other indications highlighted; however, a recent small double-blind trial in patients with Parkinson’s disease found the CBD improved quality-of-life scores.xxii
Collin, C., Ehler, E., Waberzinek, G., Alsindi, Z., Davies, P., Powell, K., Notcutt, W., O'Leary, C., Ratcliffe, S., Novakova, I., Zapletalova, O., Pikova, J., and Ambler, Z. A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis. Neurol.Res. 2010;32(5):451-459. View abstract.
Cannabis sales have been illegal since the 1970 Controlled Substances Act was passed, with the only exceptions being the products made from the "mature stalk" and "sterilized seed" of the hemp plant, which could still be sold since they contained little to no psychoactive components. Even today, federal law has not changed its stance on cannabis. On the state level, however, things have changed dramatically. As of this writing, there are 30 states that have legalized the sale of cannabis in some form, whether that be medicinally or recreationally. Because federal law continues to outlaw the production and sales of cannabis aside from the CBD oil and hemp seed oil from hemp plants, it is illegal for states that have legalized cannabis to sell products across state borders.
Cannabidiol is POSSIBLY SAFE when taken by mouth or sprayed under the tongue appropriately. Cannabidiol in doses of up to 300 mg daily have been taken by mouth safely for up to 6 months. Higher doses of 1200-1500 mg daily have been taken by mouth safely for up to 4 weeks. A prescription cannabidiol product (Epidiolex) is approved to be taken by mouth in doses of up to 10-20 mg/kg daily. Cannabidiol sprays that are applied under the tongue have been used in doses of 2.5 mg for up to 2 weeks.
CBD, or cannabidiol, is a cannabinoid found in the hemp plant. As we’ve discovered more about the human species as well as the plants that we’ve learned of the immense health value that CBD brings to the table. It has quickly become a staple supplement for millions who seek a natural alternative to dangerous pharmaceuticals, alien to nature’s perfect remedies.
Kimberly is the reference editor for Live Science and Space.com. She has a bachelor's degree in marine biology from Texas A&M University, a master's degree in biology from Southeastern Louisiana University and a graduate certificate in science communication from the University of California, Santa Cruz. Her favorite stories include animals and obscurities. A Texas native, Kim now lives in a California redwood forest. You can follow her on Twitter @kimdhickok.

A 2013 case report conducted in Canada evaluated the beneficial effects of cannabis oil on a 14-year-old female patient diagnosed with acute lymphoblastic leukemia, also known as ALL. For this particular patient, a standard bone marrow transplant, aggressive chemotherapy and radiation therapy were revoked, with treatment being deemed a failure after 34 months. She was extremely ill and severely underweight at this time.


Cannabis has been around for thousands of years and is believed to have originated in South or Central Asia. The two main species of cannabis are Cannabis sativa and Cannabis indica. Both Cannabis sativa and indica contain varying amounts of psychoactive and nonpsychoactive components. Cannabis sativa is more commonly known for its stimulatory, mental effects while Cannabis indica is more known for its relaxing, body-calming effects.
Yes! We ship our CBD oil to over 40 countries including Argentina, Austria, Australia, Belgium, Belize, Brazil, Bulgaria, Chile, China, Colombia, Costa Rica, Croatia, Cyprus, Czech Republic, Denmark, England, Estonia, Finland, France, Georgia, Germany, Greece, Guam, Guatemala, Hong Kong, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Lithuania, Luxembourg, Mexico, Netherlands, Antilles, Northern Ireland, Norway, Paraguay, Peru, Poland, Portugal, Puerto Rico, Romania, Russia,  Slovenia, South Africa, Sweden, Switzerland, U.S. Virgin Islands, Uruguay, and many others! If you require assistance completing a payment, please contact us.

The exact mechanism of action of CBD and THC is not currently fully understood. However, it is known that CBD acts on cannabinoid (CB) receptors of the endocannabinoid system, which are found in numerous areas of the body, including the peripheral and central nervous systems, including the brain. The endocannabinoid system regulates many physiological responses of the body including pain, memory, appetite, and mood. More specifically, CB1 receptors can be found within the pain pathways of the brain and spinal cord where they may affect CBD-induced analgesia and anxiolysis, and CB2 receptors have an effect on immune cells, where they may affect CBD-induced anti-inflammatory processes.
Thoughts: This is hands-down my favorite CBD oil based solely on taste. It smells great, the flavor is subtle with a good aftertaste, and it's a nice morning pick-me-up. Plus, the bottle is amazing, and it has the best dropper and lid combo. (You might laugh, but I still have a half-full bottle of CBD oil in my bathroom cabinet that I haven't been able to open for three months.)
When people cite the so-called negative effects of cannabis, they are usually due to the presence of  tetrahydrocannabinol (THC), the compound that causes the psychoactive effects. Some of these, such as paranoia and increased levels of stress, may be negated by the balancing power of cannabidiol. The chemical can help increase feelings of calm and self-awareness to make it safer for patients to use cannabis for medical treatment without risking common side effects. Since each patient reacts differently to treatment, some may experience differing effects that can occur during cannabis consumption.
A 2013 case report conducted in Canada evaluated the beneficial effects of cannabis oil on a 14-year-old female patient diagnosed with acute lymphoblastic leukemia, also known as ALL. For this particular patient, a standard bone marrow transplant, aggressive chemotherapy and radiation therapy were revoked, with treatment being deemed a failure after 34 months. She was extremely ill and severely underweight at this time.
It's important to know that although THC and CBD are the most studied components of cannabis, there are many more chemical compounds found within the plant, such as cannabigerol (CBG), cannabichromene (CBC), cannabidivarin (CBDV), tetrahydrocannabivarin (THCV), terpenes, and flavonoids. While there is still much to learn about these other chemicals, researchers in Israel have discovered that whole-plant cannabis extracts that contain these other chemicals are more beneficial than isolated extracts that contain just CBD or THC.
Evidence from animal studies have begun to characterize the details of how CBD acts in the brain, and human studies of patients with and without anxiety disorders are starting to validate CBD’s efficacy as an anti-anxiety treatment. Given the huge social and financial costs of anxiety disorders in the U.S., CBD has the potential to play a significant role in treating a myriad of anxiety-related disorders.

Epidiolex is the first FDA-approved treatment in the U.S. that contains a purified drug substance derived from marijuana -- CBD -- and the first treatment for Dravet syndrome. In September 2018 the FDA rescheduled cannabidiol from a C-I controlled substance to a C-V controlled substance, meaning it has a proven medical use but a low risk of abuse. This change allows Epidiolex to be marketed in the U.S.
^ Nadulski T, Pragst F, Weinberg G, Roser P, Schnelle M, Fronk EM, Stadelmann AM (December 2005). "Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract". Ther Drug Monit. 27 (6): 799–810. PMID 16306858.
Δ9-THC is also responsible for the pharmacological effects of cannabis, including its psychoactive properties, although other contents of the cannabis plant also contribute to this effect. In particular, CBD, a non-psychoactive phytocannabinoid common in some cannabis strains, has anti-inflammatory, analgesic, anxiolytic and antipsychotic properties.

Cannabis oil is a concentrated extract obtained by extraction of the dried flowers or leaves of the cannabis plant. It is not actually an oil, but derives its name from its sticky and oily appearance. The purpose of producing cannabis oil is to make cannabinoids and other beneficial components, such as terpenes, available in a highly concentrated form.
CBD Essence company unquestionably understands some facts about hemp oil. The proprietor Don has genuinely been around the pharmaceutical business for many years, and subsequently, he knows how to convey a quality and successful item. Every one of their oils is made utilizing CO2 extraction techniques. They maintain a strategic distance from CBD isolates, and they generally uncover lab test results to guarantee there is no substantial metals or contaminants in the oil.
It is also illegal to market CBD oil as a dietary supplement.  This is because cannabidiol is not a food ingredient (dietary ingredient) and it doesn’t have an established safety profile or history of use in the food supply. If you see a CBD product, and it is labelled as a dietary supplement, then the company is either unaware or doesn’t care about the FDA’s current position that CBD is not a legitimate dietary ingredient.
Hemp seed oil made from the industrial hemp plant contains only tiny trace amounts of THC. THC is why marijuana is illegal in so many countries and states. So, since industrial hemp oil is low in THC but contains high amounts of CBD, you can get your CBD hemp oil legally in all 50 states and shipped right to your home. You won’t get a high from CBD oil, but you will get all the health benefits of a high-quality CBD supplement.
CBD has some other very important jobs outside of the endocannabinoid system (ECS). For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A), which may explain CBD’s effects on depression and anxiety. It also acts at the peroxisome proliferator activated receptors (PPARs), which halt the proliferation of cancer cells and convey neuro- and cardioprotection. By interacting with a particular PPAR (gamma), CBD could prove to be a promising new way to prevent alzheimer’s disease and other brain disorders.
I have a slightly bulging disc in my back that has been causing neuropathy in my left leg for years. I’ve had several rounds of trigger point injections; see a physical therapist regularly, and lately a chiropractor as well. The next step for me would be to try an epidural pain block. Several of my other doctors are big proponents of the “inflammation as a cause of disease” theory and have really encouraged me to do things to reduce inflammation. Omega-3 fatty acids in particular help with this (as most Americans consume a poor ratio of omega-6 to omega-3 which can increase inflammation.) Hemp products contain phytocannabinoids, a substance that can help decrease pain and inflammation. This is full spectrum hemp oil derived from hemp seeds—meaning it contains all of the phytocannabinoids and not just one in particular. This is NOT CBD (cannabidiol) oil, although based on my research it likely contains low levels of CBD. CBD is the substance produced from hemp flowers (a plant with little to no THC—the substance that causes a high) (or marijuana flowers—a plant in the same family with significant THC) that is widely known to have medicinal purposes in pain relief, stopping seizures, etc.
After this devastating news, the family researched cannabinoids and found that they have been shown to inhibit the growth of tumor cells in culture and in animal models by modulating key cell-signaling pathways. Her family read that cannabinoids are usually well-tolerated and do not produce the generalized toxic effects of conventional chemotherapies. The family found promise in an organization that treated several cancers with cannabis oil.
Bonn-Miller also explained that it's imperative to exhaust the traditional and established front-line treatments that are available before seeking out these products. "CBD is not really a first-line treatment for anything," he said. "You don’t want situations where somebody says, 'I have cancer I'm going to forgo chemotherapy because I read something about CBD or THC helping with cancer.'" That's not a good idea, Bonn-Miller said. "Not only is the science not there, but you may end up worse off."
Tetrahydrocannabinol (THC) and cannabidiol (CBD) are two types of cannabinoids found naturally in the resin of the marijuana plant, both of which interact with the cannabinoid receptors that are found throughout the body. Although THC and CBD have been the most studied cannabinoids, there are many others identified to date including cannabinol (CBN), cannabigerol (CBG), Cannabidivarin (CBDV), and Tetrahydrocannabivarin (THCV) that can be found within the medical cannabis [10]. While both CBD and THC are used for medicinal purposes, they have different receptor activity, function, and physiological effects. If not provided in their activated form (such as through synthetic forms of THC like Dronabinol or Nabilone), THC and CBD are obtained through conversion from their precursors, tetrahydrocannabinolic acid-A (THCA-A) and cannabidiolic acid (CBDA), through decarboxylation reactions. This can be achieved through heating, smoking, vaporization, or baking of dried unfertilized female cannabis flowers.

Interestingly, CBD oil protects the body against its own euphoric stimulant. An endogenous cannabinoid, Anandamide, is produced on demand by the human body. ‘Ananda’, in Sanskrit, means ‘bliss’. Anandamide, thus, creates a runner’s high, and this is regulated by Cannabidiol. Thus, we feel falsified pleasureless, on the use of cannabidiol or CBD oil.
“THC”—the more-famous, high-inducing compound in cannabis—“works directly on the cannabinoid system, meaning it attaches to receptors and mimics some of our own internal endocannabinoids,” says Igor Grant, a professor and chair of psychiatry at the University of California, San Diego School of Medicine. But CBD’s interaction with the endocannabinoid system is subtler. “Normally, these endocannabinoid-signaling molecules are broken down by enzymes, and one thing CBD does is interfere with the actions of those enzymes.” 

A non-intoxicating cannabinoid found in cannabis. After tetrahydrocannabinol (THC), cannabidiol (CBD) is the second-most abundant cannabinoid in the plant, and has many potential therapeutic benefits, including anti-inflammatory, analgesic, anti-anxiety and seizure-suppressant properties. Cannabidiol can be sourced from both marijuana plants and hemp plants, which are legal in most countries as they contain minor amounts of THC.  

In general, though, much of the hesitation linked to using a cannabis or hemp-derived product like CBD oil comes from years of stigma. “Cannabis and hemp…were prohibited in this country starting in 1937, so there’s been [decades] of misinformation and miseducation around this plant,” Cargile says. “Really, just about everything everybody has heard…and all of the stereotypes are not true, and CBD particularly is a very safe, non-toxic alternative to many pharmaceuticals.”

Cohen has found that chronic conditions including autoimmune diseases and pain syndromes can be helped with a 6-mg under-the-tongue tincture (the fastest delivery system) or a 25-mg capsule taken twice a day. Dosages for topical products like lotions are especially hard to determine—there’s no clarity on how much CBD gets into the system through the skin.

CB2 receptors are predominantly expressed by cells in the immune system and are traceable at low-density levels in the brain (microglia, the brain stem) and in the keratinocytes of the skin. Like the CB1 receptors, they also belong to the G-protein-coupled receptors. When they are activated a signaling cascade is set into motion (inhibition of adenylate cyclase, intracellular calcium release, inhibition of the potassium efflux), which eventually leads to a modulation of neuronal excitability.


Under federal law, cannabis (from which both CBD and marijuana are derived) is illegal everywhere, although the laws against it aren’t generally enforced in states that have legalized marijuana. Some manufacturers claim that CBD culled from legally imported industrial hemp, which has little to no THC, is fine to ship across the U.S., but many experts disagree, noting that because hemp comes from the same species as marijuana, cannabis sativa, all CBD falls under the DEA’s Schedule 1 designation. “This creative interpretation of the law runs afoul of reality,” says the Brookings Institution, a Washington, DC, think tank.
It makes no sense to me that something that helps with anxiety has an irritability side effect – as a lot of my anxiety is co-mingled naturally with irritability. Further, I have noticed none of these side effects, given that if you become fatigued or sleepy, you adjust dose the next day. So I don’t call that a side effect – rather – an effect of taking too much.
Tetrahydrocannabinol (THC) is the naturally occurring compound that famously produces cannabis’ mind-altering states. The CBD compound found in the plant, however, does not have psychoactive properties. CBD produces a calming effect on the mind, making it a good treatment for people with social anxiety and other nervous disorders. When combined with THC in stronger amounts, CBD can help balance out the medication, ensuring that the user does not get too high. Oil can be slightly harder to procure and more expensive than medical marijuana flowers, depending on state laws. Smoking cannabis can be more beneficial to some people, largely depending on their condition.

CBD strains can be consumed just as you would THC strains. You can smoke or vaporize CBD-rich flower, eat a CBD-infused edible, swallow a CBD oil capsule, apply a CBD lotion, or use a CBD tincture sublingually. Hemp products also contain CBD, though it is a less efficient source and lacks the beneficial chemical diversity of cannabis-derived CBD products (more on that here).


The rosemary acts as a natural antioxidant preservative. It also supplies terpenoids, including camphene, pinene, and limonene, that support a healthy inflammatory response and promote relaxation.* Hops is a very close cousin of hemp and many of the compounds in hops are complementary to those in hemp. The hops in Hemp Oil + provides a source of the terpenoids humulon and lupulon that are synergistic with the phytocannabinoids in support of the ECS.* 

Before beginning any treatment, it is important that you consult your healthcare provider and be open and honest about your plans. Having a strong doctor-patient relationship is key to establishing trust and determining an effective treatment plan that takes into account your lifestyle. “These drugs do interact with the body,” Dr. Silberstein says. “If you’re getting funny symptoms and you’re taking something that the doctor doesn’t know about, how’s he going to help you?”
In addition to fighting inflammation in the body, CBD oil may reduce anxiety by directly affecting the brain. Studies have found that CBD actually lowers activity in the amygdala and increases prefrontal cortex activation, two parts of the brain involved in anxiety. There is also evidence that CBD is able to activate hippocampus neurogenesis, aka regenerate new neurons! This activates CB1 receptors, which has a positive balancing impact on GABA and glutamate levels, associated with reducing anxiety.
Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.

Hempseed oil is manufactured from varieties of Cannabis sativa that do not contain significant amounts of tetrahydrocannabinol (THC), the psychoactive element present in the cannabis plant. This manufacturing process typically includes cleaning the seed to 99.99% before pressing the oil. There is no THC within the hempseed, although trace amounts of THC may be found in hempseed oil when plant matter adheres to the seed surface during manufacturing. The modern production of hempseed oil, particularly in Canada, has successfully lowered THC values since 1998.[5] Regular accredited sampling of THC in Canadian hemp seed oil shows THC levels usually below detection limit of 4 ppm (parts per million, or 4 mg/kg). Legal limit for THC content in foodstuffs in Canada is 10 ppm.[6] Some European countries have limits of 5 ppm or none-detected, some EU countries do not have such limits at all.
Our family has been making healthy oils and supplements in the Pacific Northwest for nearly 30 years. As a leader in the natural foods industry, we stake our reputation on innovating and creating the quality products our customers have come to expect. And like all of our products, our Ideal CBD Hemp Oil meets the very highest standards of excellence.
In a small study published in the journal JCI Insight in 2017, researchers observed that CBD may help prevent stress-related changes in blood pressure. For the study, nine healthy male volunteers took a single dose of either CBD or placebo. Compared to those given the placebo, those treated with CBD had lower blood pressure both before and after experiencing a stressful event.
Cannabis oil refers to any concentrated extract made from cannabis. Cannabis oil can technically come from either hemp or marijuana, since both are varieties of the cannabis plant, but it typically refers to oil made from marijuana, which contains a much higher level of THC than hemp. Cannabis oil that comes from marijuana is highly regulated in the US and across the world. Federal law makes cannabis oil illegal, but cannabis oil is legal in states allowing for recreational usage, as well as states that allow for medicinal use with a doctor’s prescription.
In sport, THC has a reporting threshold of 150ng/mL, which means that if the WADA-accredited laboratories detect THC below that level in the urine, it won’t be considered a positive test. Other cannabinoids on the WADA Prohibited List don’t have a reporting threshold, meaning that the detection of even the tiniest amount in your urine will be considered a positive test.
Irie Hemp Company are sourcing their base extract from whole plant organic Oregon grown, full spectrum high CBD hemp varietals grown specifically for CBD extraction. The farm they are sourcing from in Oregon, is growing hemp under the Oregon Department of Agriculture hemp program and this hemp is being grown SPECIFICALLY for high CBD concentrations. The resultant whole plant extract is a blend of the buds and leaves of the hemp plant, rich in natural phytocannabinoids and terpenes.

Barrett Jones is a clinical pharmacologist who studied at Baylor College of Medicine, Texas. He currently works in a chemistry laboratory in Columbia University (where he also lecturers occasionally) investigating how pharmaceuticals interact with our biological systems. He specializes in and is passionate about how medication used for treating ADD and ADHD may impact long-term cognitive abilities. He has written many papers and is often consulted in a number of lawsuits against pharmaceutical companies.
While the science behind CBD oil assuaged many of my concerns, Charlotte Figi's inspiring story was the kicker. Figi, a 6-year-old girl diagnosed with a rare and resistant form of epilepsy known as Dravet syndrome, was actually placed on hospice care and given a "do not resuscitate" order when her parents, desperate and frustrated with pharmaceutical medication, considered medical marijuana. Charlotte is now 99% seizure-free since she began supplementing with Charlotte Web's CBD oil, which the brand named after Figi.
Extinction learning: One way we get over anxiety is through “extinction learning,” or learning to let go of triggers when there’s nothing left to fear. These experiments often train test subjects to associate something harmless with something painful, and then measure how long it takes to stop fearing the harmless trigger after they stop delivering pain. This is particularly relevant for people suffering from PTSD:
Throughout recent years, cannabis oil has been utilized as a viable treatment for anxiety and depression. Moreover, it is continually being looked into by researchers. Truth be told, the impacts of CBD on anxiety is at present thought to be a standout amongst the most captivating and well-funded sectors of current cannabis research; if development proceeds in the way that it has in the course of the past years, at that point we will unquestionably expand exceptionally compelling means by which oils for anxiety and depression can be utilized as a viable treatment.
John Staughton is a traveling writer, editor, and publisher who earned his English and Integrative Biology degrees from the University of Illinois in Champaign, Urbana (USA). He is the co-founder of a literary journal, Sheriff Nottingham, and calls the most beautiful places in the world his office. On a perpetual journey towards the idea of home, he uses words to educate, inspire, uplift and evolve.
Ringo’s Gift: This cultivar is named after the cannabidiol pioneer, Lawrence Ringo. Ringo’s Gift is a cross between two other CBD-rich strains, AC/DC and Harle-tsu. Its CBD to THC ratio varies from 1:1 to 22:1, but it consistently favors CBD. Ringo’s Gift smells of earthy pine and promises full-bodied relaxation in tandem with calming cerebral effects which, together, silence pain and anxiety.
We're on the edge of a CBD explosion. The U.S. market for CBD products is estimated to be worth $2.1 billion by 2020, up 700 percent from 2016; the World Anti-Doping Agency removed CBD from its list of banned substances; the Food and Drug Administration approved an epilepsy medication containing CBD oil for the first time, causing the U.S. Drug Enforcement Administration to shift its stance — albeit very slightly — on CBD.
Hempseed oil is manufactured from varieties of Cannabis sativa that do not contain significant amounts of tetrahydrocannabinol (THC), the psychoactive element present in the cannabis plant. This manufacturing process typically includes cleaning the seed to 99.99% before pressing the oil. There is no THC within the hempseed, although trace amounts of THC may be found in hempseed oil when plant matter adheres to the seed surface during manufacturing. The modern production of hempseed oil, particularly in Canada, has successfully lowered THC values since 1998.[5] Regular accredited sampling of THC in Canadian hemp seed oil shows THC levels usually below detection limit of 4 ppm (parts per million, or 4 mg/kg). Legal limit for THC content in foodstuffs in Canada is 10 ppm.[6] Some European countries have limits of 5 ppm or none-detected, some EU countries do not have such limits at all.
Thank you. I am 81 and started the CBD drops night and morning. I sleep better and no longer suffer the excruciating pain from diverticulitis. I saw somewhere that for my asthma I need the THC so got some (totally illegal here in South Africa). I think it is helping. The diagnosis of COPD was made some years ago and as a health psychologist I do all I can to remain healthy for my 97th birthday!! (Both my grandmother and greatgrandmother did so I believe I will too).
In addition to fighting inflammation in the body, CBD oil may reduce anxiety by directly affecting the brain. Studies have found that CBD actually lowers activity in the amygdala and increases prefrontal cortex activation, two parts of the brain involved in anxiety. There is also evidence that CBD is able to activate hippocampus neurogenesis, aka regenerate new neurons! This activates CB1 receptors, which has a positive balancing impact on GABA and glutamate levels, associated with reducing anxiety.
The ECS is responsible for setting the baseline activity levels of our immune system and nervous system, which then work to maintain our health. When the ECS falls out of whack, the systems that are regulated by it can begin to malfunction. CBD promotes the normal health and function of the endocannabinoid system, so it’s possible that CBD can help to alleviate the symptoms of conditions that are caused by dysfunction of the endocannabinoid system.
Multiple sclerosis (MS). There is inconsistent evidence on the effectiveness of cannabidiol for symptoms of multiple sclerosis. Some early research suggests that using a cannabidiol spray under the tongue might improve pain and muscle tightness in people with MS. However, it does not appear to improve muscle spasms, tiredness, bladder control, the ability to move around, or well-being and quality of life.
It turns out that this unpredictability comes mainly from variations in the quantities and ratios of phytocannabinoids and synergistic terpenes. Too much THC can overstimulate the body’s CB1 receptors, while THC’s non-intoxicating sister molecule, cannabidiol (CBD), can directly and indirectly counteract the anxiety people experience from too much THC. Different cannabis strains have different concentrations of these two molecules — which is one reason for vastly different anxiety responses.

The studies done on CBD oil have a pretty wide dose range (anywhere from a few milligrams to hundreds of milligrams). I suggest starting at the lower end (around 10 milligrams) and slowly increasing over a few weeks or months to see what works for you. Some people also do well with splitting the dosage throughout the day instead of taking the dose all at once. As with everything, it is always a good idea to talk with your prescribing doctor if you are on any medications. CBD is generally very safe, but there are some pharmaceutical medications CBD oil could potentially interact with and increase or decrease the pharmaceutical drugs' effectiveness. 

Most CBD oils are available in round-number concentrations such as 250mg, 500mg, and 1,000mg. While these strengths accommodate many CBD users, they may not be sufficient for those with preferences that fall outside round numbers. NuLeaf Naturals offers a less conventional selection of concentrations: 240mg, 725mg, 1,450mg, 2,425mg, and 4,850mg. This range ensures that most users will find a strength that works for them.


Some users speculate about appropriate dosages or methods of application—including whether or not a small amount of THC boosts CBD’s effects, or whether different methods of administration lead to quicker or more significant effects. Some CBD producers also claim that it has a cumulative effect, and so needs to be used regularly to produce a benefit. But Grant says it’s tough to say at this point exactly how people should (or shouldn’t) be using CBD.
Word of Caution: Although this list clearly shows that cannabis essential oil can be an effective remedy for many common health conditions, it is still a potent chemical substance extracted from a plant with psychotropic substances. Therefore, you should always be very careful while using such an essential oil, including the amount you use and the conditions under which you use it. Speak to a professional about mixing essential oils and present medications before adding any new elements to your health regimen. Also, the use of cannabis is restricted/banned in many countries, so consult a local health specialist before use.
Extinction learning: One way we get over anxiety is through “extinction learning,” or learning to let go of triggers when there’s nothing left to fear. These experiments often train test subjects to associate something harmless with something painful, and then measure how long it takes to stop fearing the harmless trigger after they stop delivering pain. This is particularly relevant for people suffering from PTSD:
Hemp oil or hempseed oil is obtained by pressing hemp seeds. Cold pressed, unrefined hemp oil is dark to clear light green in color, with a nutty flavour. The darker the color, the grassier the flavour. It should not be confused with hash oil, a tetrahydrocannabinol-containing oil made from the Cannabis flower, hailed by some[1] for its medicinal qualities.[2]
Disclaimer: This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.

In September 2018, following its approval by the FDA for rare types of childhood epilepsy,[14] Epidiolex was rescheduled (by the Drug Enforcement Administration) as a Schedule V drug to allow for its prescription use.[15] This change applies only to FDA-approved products containing no more than 0.1 percent THC.[15] This allows GW Pharmaceuticals to sell Epidiolex, but it does not apply broadly and all other CBD-containing products remain Schedule I drugs.[15] Epidiolex still requires rescheduling in some states before it can be prescribed in those states.[65][66]


Therefore, ingesting 2,000 mg of CBD oil daily would result in a maximum consumption of 6 mg of THC, which would cause a positive marijuana urine test approximately 23 percent of the time. It’s important to keep in mind the amount of CBD consumed. Although unlikely, it is possible for those who take CBD to fail drug tests if they are taking unusually high doses.

Do not confuse cannabis oil extracts(marijuana) with hemp seed oil, which is the oil expeller pressed from hemp seed and not chemically extracted from cannabis leaves and flowers.  Marijuana oil extracts on the other hand contain from 5-20% THC. WE DO NOT CARRY THIS OIL.  ALL OUR OILS ARE LEGAL IN THE UNITED STATES. All of our Oils come from the Industrial Hemp Plant and are legal in all 50 states. 


Medical marijuana in the U.S. is controlled at the state level. Per federal law, cannabis is illegal as noted in the Controlled Substances Act, but the federal government has stated they will not actively prosecute patients and caregivers complying with state medical marijuana laws. However, use of medical marijuana outside of the state laws for illegal use or trafficking will not be tolerated by state or federal government. 

Collin, C., Ehler, E., Waberzinek, G., Alsindi, Z., Davies, P., Powell, K., Notcutt, W., O'Leary, C., Ratcliffe, S., Novakova, I., Zapletalova, O., Pikova, J., and Ambler, Z. A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis. Neurol.Res. 2010;32(5):451-459. View abstract.

While there are many different pathways driving the positive health benefits of CBD, the center of its awesome abilities seems to be that CBD is a very effective natural anti-inflammatory. Chronic inflammation is really the commonality between most (and by most, I mean basically all) chronic health problems that we face today as a modern society. Cancer, heart disease, diabetes, autoimmune conditions, digestive issues, and hormonal problems are all inflammatory in nature. What the heck, right?


I’ve been on anti-depressants for 11 years since having a stroke and having to stop taking estrogen. I started on Zoloft, then celexa, then Effexor. I’ve been having bad blurry vision for a few years that has my eye dr stumped. Finally my primary doctor thought it could be the Effexor since that is one of the side effects. So we decided that I would wean off the Effexor and try Wellbutrin instead. I lowered the amount of Effexor over 3 weeks till I wasn’t taking it any longer but started the Wellbutrin the last week of taking Effexor. After 3 days of no Effexor the withdrawals seemed to hit me. Headaches, nausea, extremely emotional, and bad dizziness. I had an important event to go to on day 3 of no Effexor so I took a low dose (37.5 mg) hoping to get me through the night. I felt decent for a couple days then boom, the withdrawal symptoms came on fully again. So I decided I would just try to go off both the Effexor and Wellbutrin because I didn’t want to go through this again and really wanted to see if I could handle life without them. Well it’s been a week without any Effexor but the dizziness and emotional outrages are still going on. I’ve been using Bonine (motion sickness) which does seem to help a little. My daughter mentioned the CBD oil which I was totally against at first but after doing a lot of research I am now quite interested in it.

Inhibited liver function: The liver regulates the way different drugs are metabolized within the body; this process is known as hepatic drug metabolism. Higher-than-average doses of CBD oil can slow the hepatic drug metabolism process. As a result, users may not be able to process other drugs as quickly. This is particularly concerning for CBD oil users who also take prescription medications.
It is important to note that the federal government still considers cannabis a dangerous drug and that the illegal distribution and sale of marijuana is a serious crime. Under the Controlled Substances Act (CSA), marijuana is still considered a Schedule 1 drug. Cultivation and distribution of marijuana are felonies; possession for personal use is a misdemeanor; possession of “paraphernalia” is also illegal. Cultivating 100 plants or more carries a mandatory minimum sentence of five years according to federal statutes.
The extract known as CBD oil sold in the U.S. falls into one of two categories. Crystalline isolate exclusively contains CBD, as other cannabinoids have been removed; full spectrum oil, on the other hand, retains THC and other cannabinoids, and is only sold in states where marijuana use has been legalized. CBD oil can be consumed several different ways, including ingested capsules and food products, vaporizing, tinctures, and topical creams. The soporific effects of CBD oil are linked to its concentration; low-concentration oils will produce minimal effects, while high-concentration oils will produce strong effects.

This article may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties.


Hemp and Marijuana come form the same plant family, but are completely different in function, cultivation and application. Marijuana generally has a high level of THC (a psychoactive compound that makes you feel “high”) and is used for medicinal or recreational purpose. Hemp contains a negligible amount of THC (but is high in CBD) and is used in dietary supplements, skin products, clothing and paper.
Nutiva began in 1999 as an idea in the mind of John W. Roulac, the author of four books on home composting and industrial hemp. Nutiva is the third successful business John has founded since jump-starting the modern home-composting movement in the early 1990s with his best-selling book, Backyard Composting. That book has sold more than a million copies worldwide.
In April 2018, a Food and Drug Administration advisory panel unanimously recommended approval of Epidiolex (cannabidiol oral solution) for the treatment of two rare forms of epilepsy - Lennox-Gastaut syndrome and Dravet syndrome, which are among the two most difficult types of epilepsy to treat [18, 16]. Epidiolex was granted Orphan Drug designation as well as Fast Track Approval from the FDA for further study in these hard to treat conditions. Notably, phase 3 clinical trials of Epidiolex have demonstrated clinically significant improvement in Lennox-Gastaut syndrome and Dravet syndrome [17]. On June 25th, 2018, Epidiolex was approved by the FDA to be the first CBD-based product available on the US market.
Cannabidiol is a chemical in the Cannabis sativa plant, also known as marijuana. Over 80 chemicals, known as cannabinoids, have been identified in the Cannabis sativa plant. While delta-9-tetrahydrocannabinol (THC) is the major active ingredient, cannabidiol makes up about 40% of cannabis extracts and has been studied for many different uses. According to the U.S. Food and Drug Administration (FDA), because cannabidiol has been studied as a new drug, products containing cannabidiol are not defined as dietary supplements. But there are still products labeled as dietary supplements on the market that contain cannabidiol. The amount of cannabidiol contained in these products is not always reported accurately on the product label.
Hemp oil can come from the flower, leaves, stock or seeds. If it comes from the seed there are no cannabinoids found. If it comes from the rest of the plant cannabinoids are found. Hemp extract usually refers to either CBD or oil from the stock, flower, or leaves. Our Virgin cannabis sativa hemp oil is a hemp seed oil, and our Premium hemp oil products, have hemp oil from the stem of the plant (which is listed in milligrams on the bottle) It also has hemp seed oil in the bottle to act as a carrier oil. Our Hemp seed oil is a cold pressed seed oil, and our Premium hemp oil that comes from the stem is Co2 extracted.
The product was shipped as I expected, packed well, and delivered on time. The cost factor is also appealing. After researching products, I have found something more affordable than I have come across so far. That will help to keep me loyal to the product. It is a very saturated, competitive field out there for this product, so if it works, and the price is affordable, I will buy it over other products, who wouldn't? I hope as laws change, the cost will come down even more. And if you are wondering for yourself about using this kind of product for your anxiety, I would tell you to give it a try. Start off with a low type dose, and see what works for you.
So far, I am very pleased with this product. I have been trying this product to address issues I have dealt with for many years now. With laws the way they are right now, I am very pleased to be able to pursue this course of treatment, which is mainly anxiety, mild panic attacks...... I still can say for certain, but the CBD method seems to be working for me. And I'm going to continue on this path of addressing my issues, as my doctor would, if laws allowed him to.
I have been totally off the effexor and all anti-depressants for 2 weeks now. The dizziness is getting much better however my emotions/agitation are horrible. I cry at everything and am extremely crabby/agitated. I realize most of this has to do with the withdrawal. I really want to see this through to find out if I can live without anti-depressants but at the same time I know it's very hard on my family. I have another doctor appt beginning of April and she says that if I don't feel better by then I most likely will need to go back on an anti-depressant. For the most part I agree with her. My hopes of proving her wrong as getting slim however. I'd like to know how long it took some of you who have withdrawn from anti-depressants to feel somewhat 'normal' or you knew you had to go back on them? I guess I'm asking if another month is a good amount of time for me to determine what I should do. In some ways I feel like I should start on them again now but I'm not going there yet? BTW, I am in no way feeling suicidal. Mornings seem to be my worst time and by early evenings I feel somewhat better – is this strange too? I haven't tried the CBD living water yet but did find a place near me to get it. Just havent had the time to get there. I also have the Ativan which I take one night to help with sleep. I'm trying not to take it unless really necessary. Tomorrow I have a huge even that my husband and I are in charge of so I'm planning to take an Ativan in the morning to get me through the day without falling apart (crying scene) in front of everyone (or yelling at them) :)! Thanks for all your input!!
A review published in 2017 in the journal Frontiers in Pharmacology described how CBD may work to protect the hippocampus — the part of the brain responsible for several important functions, such as learning, memory and navigation — during times of stress, and may also help prevent brain-cell destruction that results from schizophrenia. Another 2017 review published in the journal Annals of Palliative Medicine summarized a handful of studies that suggest cannabis oils containing THC or CBD, or both, may help with chronic pain management, but the mechanism is unclear.
×