While it was originally believed that THC is a breakdown product of CBD, it is now known that both THC and CBD are actually metabolites of their decarboxylated acidic forms, THCa and CBDa. These acidic precursors are decarboxylated (essentially dried) by heat or extraction to produce THC and CBD; only then do they become psychoactive.The compound has medicinal benefits without the “high” that some patients do not desire. This makes CBD appealing to patients who are looking for an alternative to their current meds, which often have opiate-like effects.
We’re proud to be present at Cannabis Europa; ‘the foremost arena to share knowledge and shape the future of medicinal cannabis in Europe’. Together with Nastasia Bach (Pivot Regulatory), Alex Hearn (Senzer), Jason Moscovici (ROBIC) and pharmaceutical consultant Sofia Sanz our Founder and CEO Tjalling Erkelens discusses ways to find common ground between the pharma world and the medicinal cannabis industry. ... See MoreSee Less

Because it takes a significantly larger amount of hemp stalks to produce hemp oil, there is an increased risk of contamination of toxins contained within the plant. This is a result of hemp's strong bio-accumulator properties, where it pulls toxins from the soil it grows in. Many hemp oils are also known to lack the full spectrum of terpenes and other cannabinoids that are believed to act synergistically with the CBD, meaning that consumers receive less of a benefit. That being said, there are some brands that test rigorously to make sure that the CBD content, as well as the terpenes and other cannabinoids, are up to par. It's a good sign if they offer to provide a certificate of analysis, which will tell you what kind of compounds are in the hemp oil and in what concentrations
Cannabidiol (CBD) is a subclass of Phytocannabinoids and one among one twenty cannabis compounds. It is hailed for its ability to be meditative, without causing a euphoric high. This non-addictive miracle cannabinoid has been the talk of the town and the core of numerous experiments. The anti-inflammatory properties of CBD have inspired the marketing of its by-products, such as CBD oil, for pain relief and relaxation.
The short answer: Using products with CBD oil — or CBD oil itself, for that matter — will not get you high. “CBD hemp oil is made from the flowers, leaves and stalks of hemp that contains high amounts of CBD, but low traces of tetrahydrocannabinol (THC), which is commonly found in a cannabis plant,” Carqueville says. THC is the psychoactive element of marijuana.
CBD has been shown to act as a negative allosteric modulator of the cannabinoid CB1 receptor, the most abundant G-Protein Coupled Receptor (GPCR) in the body [5]. Allosteric regulation of a receptor is achieved through the modulation of the activity of a receptor on a functionally distinct site from the agonist or antagonist binding site. The negative allosteric modulatory effects of CBD are therapeutically important as direct agonists are limited by their psychomimetic effects while direct antagonists are limited by their depressant effects [5].

To be fair, the paucity of data about CBD’s efficacy and safety in part reflects the federal government’s irrational restrictions on cannabis research. Because cannabis is classified as a Schedule 1 drug, you need a license from the Drug Enforcement Administration to research it and, until two years ago, you could use only the cannabis grown at the University of Mississippi.


Yet another benefit of essential fatty acids is mood health. Several studies have shown that Omega 3 supplementation can improve symptoms in bipolar disorder. Others have found improvements in. This could be because essential fatty acids are critical to maintaining brain function.  Endocannabinoids are also essential for mood. The endocannabinoid system regulates the release of neurotransmitters, some of which play major roles in conditions like depression and anxiety. As mentioned previously, endocannabinoids are made from fat. Consuming extra essential fatty acids gives your body the ability to produce these lipids.
By 1942, cannabis was removed from the U.S. Pharmacopoeia because of persistent concerns about its potential to cause harm. In 1951, Congress passed the Boggs Act, which included cannabis with narcotic drugs for the first time. In 1970, with the passage of the Controlled Substances Act, cannabis was classified as a Schedule I drug, giving it no accepted medicinal use.
LEGAL NOTICES: Care By Design products have not been evaluated by the Food and Drug Administration (FDA). This information is not intended to diagnose, treat or cure any disease. This information should not be interpreted as medical advice or treatment. You should consult your physician or other health care professional before starting any medication or supplements. Further, Care By Design does not manufacture, sell or distribute any products that are in violation of California State Law. 

NIDA provides research-grade marijuana for scientific study. The agency is responsible for overseeing the cultivation of marijuana for medical research and has contracted with the University of Mississippi to grow marijuana for research at a secure facility. Marijuana of varying potencies and compositions is available. DEA also may allow additional growers to register with the DEA to produce and distribute marijuana for research purposes. 

Some of the conditions cannabis oil has been used for include: cancer, diabetes, crohn's disease, gout, pain relief, Glaucoma, Opioid Dependence, treating alcohol abuse, epilepsy, psoriasis, anorexia, asthma, adrenal disease, inflammatory bowel disease, fibromyalgia, rheumatoid arthritis, pain, migraines, Dravet syndrome, Doose syndrome, Multiple sclerosis. 
Zatural: Our Premium hemp oil drops, which contain full spectrum hemp oil, is great for assisting with general pain, inflammation, and anxiety. For legal reasons Zatural cannot make any claims that our products can cure or treat any type of medical diagnosis. Our Premium hemp oil also contains hemp seed oil, which is rich in omegas. You may find studies online that talk about how omegas can help cholesterol and blood pressure.
Anxiety disorders are the most common mental health concern in the United States. An estimated 30 percent of adults in the United States (that's 66 million people) and an estimated 25 percent of teenagers and preteens are affected by anxiety. As a functional medicine practitioner, I see many people who struggle with anxiety and panic attacks, and from these statistics, it should be no surprise. But just because something is common doesn't make it normal. Fortunately, new insights into the cause of anxiety may help with the development of more effective treatment options.

Infusions: Research and opportunity have driven chefs and chemists to infuse CBD into all sorts of readily usable products, such as edibles to elixirs, sublingual sprays, capsules and even topicals. Much like concentrates, each infusion sports specific combinations or isolations of CBD, THC, and other cannabinoids, allowing users to pick and choose products that suit their exact needs. CBD topicals, for example, are incredibly effective when applied to surface-level problems like bruises, joint aches, and headaches, and have been scientifically proven to successfully combat skin-based issues including pruritus with far broader implications.


I was pleasantly surprised how much this stuff helps my anxiety! My heart rate and blood pressure have both lowered since taking this in the evenings. Taste is not bad either. I normally take CBD oil and I was worried this would not be strong enough but I tried it because it is less expensive! Glad I did. If you have anxiety or headaches I recommend trying this Hemp oil!

It’s also important to select CBD oil products based on your concentration preferences. Some forms of CBD oil – such as vapors and tinctures – normally have higher-than-average concentrations, whereas sprays and topicals tend to have lower concentrations. Remember: higher concentration means more pronounced effects, but not necessarily mean higher quality.
Cannabis sales have been illegal since the 1970 Controlled Substances Act was passed, with the only exceptions being the products made from the "mature stalk" and "sterilized seed" of the hemp plant, which could still be sold since they contained little to no psychoactive components. Even today, federal law has not changed its stance on cannabis. On the state level, however, things have changed dramatically. As of this writing, there are 30 states that have legalized the sale of cannabis in some form, whether that be medicinally or recreationally. Because federal law continues to outlaw the production and sales of cannabis aside from the CBD oil and hemp seed oil from hemp plants, it is illegal for states that have legalized cannabis to sell products across state borders.
As the benefits of CBD continue to become known, growers are modifying their crops to account for more cannabidiol and less tetrahydrocannabinol to create stronger medicinal plants. Some politicians believe that all plants with THC should be kept illegal, and as CBD plants become more commonly produced, doctors remind them that both compounds have certain benefits to be had by patients. The anti-nausea and appetite stimulating properties of THC make it an optimal treatment for some patients, depending upon their conditions and symptoms. Research also shows that the two compounds work best when together. 

One study comparing the effects of THC and CBD even found that, while THC increased anxiety by activating the neurotransmitters involved in the "fight or flight" response, CBD actually repressed autonomic arousal—or the nervous system response associated with sudden increases in heart rate or respiration. In other words, CBD is ideal for people looking to relax and unwind—not get out of their minds.
After seasonal harvests of specific cultivars, these high-CBD hemp crops are put through a specialized solvent-free extraction process to yield a hemp oil that is naturally high in cannabidiol. This pure hemp extract is then tested for safety, quality, and cannabinoid content before being exported to our processing facilities in the United States. Importing any cannabis or hemp product into the United States is a complicated and serious task, so we leave nothing to chance before our high-CBD hemp oil makes its journey across the Atlantic Ocean.
CBD products that don't contain THC fall outside the scope of the U.S. Drug Enforcement Agency's (DEA) Controlled Substances Act, which means CBD products are legal to sell and consume as long as they don't have THC. That's likely one of the reasons why CBD products, including CBD oil, are becoming more socially acceptable and increasingly popular. In 2016, Forbes reported that CBD products are expected to be a $2.2 billion industry by 2020.
NuLeaf Naturals CBD oil tinctures are all full spectrum; it is 100% organic and never made with herbicides, pesticides, or chemical fertilizers. The brand offers a full spectrum pet CBD oil tincture, as well. NuLeaf Naturals offers free shipping to all 50 states; the brand’s products are also sold in more than 1,000 retail locations across the country.
CBD edibles are foods and beverages infused with CBD for oral consumption, and they are immensely popular thanks to their delicious taste as well as their soothing effects. From CBD fruit rolls to CBD-infused coffee, CBD edibles include a wide array of shapes, dosages, and mouthwatering flavors. CBD edibles offer an easy and discreet way to never forget your daily dose of CBD. Besides their fun and fruity taste and appearance, Green Roads CBD Edibles offer all the benefits of CBD in a convenient 30-day supply so you’ll never run out whether you need a short-term fix or long-term relief.

I first encountered CBD while on sabbatical a few years back. As I drove up the Oregon Coast Highway, it was hard to miss all the cannabis shops along the Pacific. I stopped in one, perused the menu, and selected two marijuana specials — Nine-Pound Hammer and Trainwreck — and some CBD gummy bears. The cannabis was, well, as advertised, and the CBD candy, as far as I could tell, was a fruit-flavored placebo.

Some states offer cannabis for medical conditions, and this may require a medical note or proof of injury and illness. You can also join a collective, which is a group of patients who grow and share medical cannabis with each other. If you are using cannabis oil, it’s so important to make sure it’s purchased through a reputable company that sells pure and lab-tested oils. If you’re wondering how to make cannabis oil, you should first make sure this is legal in your state. Some people also like to make cannabis coconut oil, which is basically cannabis-infused coconut oil.
Hemp Oil Complex™ is a combination of well-balanced polyunsaturated fatty acids (PUFAs, omega-3 oil) delivering essential fatty acids needed for the formation of specialized lipid mediators for a healthy immune response. Hemp oil and omega-3 oil may support the resolution phase of the inflammatory process by providing PUFAs which are known to be precursors to endocannabinoids. Additionally, Brassica (TrueBroc®) is an important phytonutrient providing antioxidant support by activating the Nrf2/ARE pathways.
John Staughton is a traveling writer, editor, and publisher who earned his English and Integrative Biology degrees from the University of Illinois in Champaign, Urbana (USA). He is the co-founder of a literary journal, Sheriff Nottingham, and calls the most beautiful places in the world his office. On a perpetual journey towards the idea of home, he uses words to educate, inspire, uplift and evolve.
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