Although cannabidiol still requires further study to know all of its health benefits, scientists have been able to pinpoint some of the medical uses of the compound. CBD can help treat nausea and vomiting, making it a useful choice for cancer patients. Cannabidiol may also help shrink the growth of cancer and tumors. It may help people who suffer from psychoses, anxiety and depression. Inflammation and neurodegenerative effects, such as those with Alzheimer’s disease, may be reduced through the use of CBD. Oil made from the compound could even be used to treat forms of epilepsy in children. Its calming effects are also useful for people with social anxiety disorder.
It is clear that CBD oil has a number of functions in pain relief and regulation. However, there are a few arguments that are worth considering. One is the use of CBD oil on children. Although proven to be a player in autism-symptom mitigation, the influence of CBD oil on the developing brain has yet to be deemed unintrusive. It is still not recommended that CBD be used extensively on children. The recommended dosage of CBD oil for children and adults, both, must be determined in consultation with a doctor.
CB2 receptors are predominantly expressed by cells in the immune system and are traceable at low-density levels in the brain (microglia, the brain stem) and in the keratinocytes of the skin. Like the CB1 receptors, they also belong to the G-protein-coupled receptors. When they are activated a signaling cascade is set into motion (inhibition of adenylate cyclase, intracellular calcium release, inhibition of the potassium efflux), which eventually leads to a modulation of neuronal excitability.
Understanding CBD’s analgesic, or pain-relieving, interactions with the ECS can shed light on CBD’s other interactions and effects. Importantly, the ECS participates in our bodies’ pain processing, but when CBD is introduced to our ECS, it stops the body from absorbing a pain-regulating compound known as anandamide — one of our body’s’ own natural cannabinoid molecules. Inhibiting the absorption of this compound shunts excess quantities into the bloodstream that in turn reduces pain. One study has revealed that CBD targets alpha-3 (α3) glycine receptors to suppress chronic pain and inflammation associated with dysfunctional glycine receptors, which are an important target for pain processing in the spine. In both humans and animal models, CBD has been shown to have a variety of anti-inflammatory properties. 

At sufficient doses (400-600 mg), CBD can alleviate situational anxiety, such as public speaking. Interestingly, cannabis cultivars, or strains, that are high in CBD and low in THC are better than other cultivars for alleviating depression. But when used over a long period of time, any kind of cannabis could make depression worse.  Although clinical trials in people haven’t yet been completed, there is very compelling “petri dish” evidence that CBD can reduce inflammation, for painful conditions such as Crohn’s disease, and fight some cancerous tumors. There is a massive amount of scientific research being done on CBD right now, and we are likely to see many medical breakthroughs in the next decade.
Perhaps it’s because many people have romantic and misplaced notions about nature. Some even point out that we come hard-wired with cannabinoid receptors in our brains and they must have a purpose, so why not use them? This is not exactly a persuasive argument: Nature endowed us with our own cannabinoids, so unless you have a deficiency of them or sluggish receptors, you really don’t need supplementation.

CBD oil and cannabis oil are both known to reduce the symptoms and side effects of cancer. The presence of both THC and CBD helps in treating the pain associated with cancer. According to research done by Hansen M., Medical University of Vienna, Vienna, Austria, it also treats the side effects of chemotherapy including nausea, vomiting, and anxiety.
Third-party testing: Once a CBD oil is manufactured, CBD oil companies will often submit their products for third-party tests, which are conducted by non-company personnel to ensure the product is safe for public consumption and meets quality standards.CBD oils should always be accompanied with information about third-party tests; best practice is to avoid oils that do not supply these details.

It’s thought that CBD might affect your health by attaching to receptors in the body’s endocannabinoid system—a complex biological system involved in maintaining certain aspects of your health. Emerging research shows that endocannabinoids may play a role in regulating such functions as memory, sleep, and mood, as well as metabolic processes like energy balance.
Hemp oil is a great source of high-quality nutrients and has a long history of use in Eastern culture as a multi-purpose natural remedy. Despite its widespread popularity, prejudice related to its association with Marijuana it has kept it from common use in the West. While Hemp oil contains virtually no THC (the psychoactive element in cannabis) hemp oil is still concerning to some. Thankfully, education is prevailing and the market for hemp oil is growing in the United States, with an increasing number of people seeking it out for its reported health benefits.
One of the most experienced practitioners in this field is Los Angeles physician Bonni Goldstein, who has used the compound to treat dozens of children with intractable epilepsy. She says about half of these patients have seen a significant drop in the number of seizures. “Used in the right way, with the right patient, CBD is extremely powerful,” she says.

When people cite the so-called negative effects of cannabis, they are usually due to the presence of  tetrahydrocannabinol (THC), the compound that causes the psychoactive effects. Some of these, such as paranoia and increased levels of stress, may be negated by the balancing power of cannabidiol. The chemical can help increase feelings of calm and self-awareness to make it safer for patients to use cannabis for medical treatment without risking common side effects. Since each patient reacts differently to treatment, some may experience differing effects that can occur during cannabis consumption.

"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia. 

Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification (PubMed:18826956, PubMed:18695040). Also activated by heat, low pH, citrate and phorbol esters (PubMed:18826956, PubMed:18695040). Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism (PubMed:12724311, PubMed:18826956). Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers (By similarity). Acts as a regulator of intracellular Ca(2+) in synoviocytes (PubMed:19759329). Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8 (PubMed:19759329). Together with PKD2, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). Negatively regulates expression of PPARGC1A, UCP1, oxidative metabolism and respiration in adipocytes (By similarity). Regulates expression of chemokines and cytokines related to proinflammatory pathway in adipocytes (By similarity). Together with AQP5, controls regulatory volume decrease in salivary epithelial cells (By similarity). Required for normal development and maintenance of bone and cartilage (PubMed:26249260).
A: Our Hemp Oil is regulated to contain no levels of THC as per the legal limits of the State of Idaho. Our CBD Oil is also tested and contains no levels of THC. Our Hemp Oil and CBD Oil are both 100% from the Cannabis plant (save the Peppermint Essential Oil Flavoring and Stevia in our Peppermint option). We do not dilute or use any fillers such as Medium Chain Triglycerides (MCT), Vegetable Glycerin, or other fillers.  We do offer our CBD Oil in a variety of strengths to suit everyones needs starting at Regular Strength, 3X Strength, & 5X Strength. Click the below image to see more specific to Zatural CBD Oil and Hemp Oil.
CBD is short for cannabidiol, a cannabinoid compound that is found in hemp and marijuana. Both hemp and marijuana are part of the plant family known as Cannabis. The main difference between marijuana and hemp is the level of THC in each. THC, like CBD, is a cannabinoid compound. There are 60 different known cannabinoids, but THC is the most well-known—the Beyoncé of cannabinoids, if you will. The reason THC is so famous is because it's associated with the psychoactive high that people experience after smoking or ingesting weed.
Endocannabinoids are organically produced by the human body, generated by the endocannabinoid system. Endocannabinoids have been found to help in the regulation of sleep, pain and the responses of the immune system. Cannabis scientists have been investigating the role of physiological cannabinoids in tissue recovery and disease. It is fascinating that the endocannabinoids activate the same receptors as the psychoactive THC.
CBD Living Water is expensive at $5.00 per bottle with 2 servings. It has no flavor (the tincture had a sweet weird flavor I didn't like) and is easy to drink. I only used 4 bottles to help me through my withdrawal. I don't use it now, but I will if I have anxiety in the future. I am impressed with how helpful it was in my withdrawal. I think it would help in withdrawal from cigarettes too. I did that 34 years ago though.
No, hemp oil is not the same as cannabis oil. All-natural hemp oil is obtained by cold pressing of hemp seeds whereas cannabis oil is obtained by separating the resins from cannabis flowers. Their uses and chemical composition are quite different. Cannabis oil is much higher in THC (tetrahydrocannabinol) content, which has certain effects, whereas hemp oil tends to be higher in CBD (cannabidiol) levels.

Hemp Oil Complex™ is a combination of well-balanced polyunsaturated fatty acids (PUFAs, omega-3 oil) delivering essential fatty acids needed for the formation of specialized lipid mediators for a healthy immune response. Hemp oil and omega-3 oil may support the resolution phase of the inflammatory process by providing PUFAs which are known to be precursors to endocannabinoids. Additionally, Brassica (TrueBroc®) is an important phytonutrient providing antioxidant support by activating the Nrf2/ARE pathways.
Extinction learning: One way we get over anxiety is through “extinction learning,” or learning to let go of triggers when there’s nothing left to fear. These experiments often train test subjects to associate something harmless with something painful, and then measure how long it takes to stop fearing the harmless trigger after they stop delivering pain. This is particularly relevant for people suffering from PTSD:

For people who suffer from insomnia, constant anxiety during the night or simply struggle to get a sound, restful night of undisturbed sleep, cannabis sativa essential oil may work like a charm. However, according to a research report published by Dr. Ethan Russo, Director of Research for the International Cannabis and Cannabinoids Institute, terpenoids produce an “entourage effect”.

In general, the human body has specific sites that are allotted to cannabinoids, called the cannabinoid receptor sites. Receptors are mechanisms to which the cannabinoids naturally present in the human body as well as the ones artificially ingested/ applied attach themselves. There are two kinds of receptors for cannabinoids, the CB1, and the CB2. While the CB1 receptors are present in the brain, the CB2 receptors can be found in the immune system.
Due to the need for confirmatory studies to verify the clinical benefit coupled with the promising nature of the clinical evidence, Sativex was also given a Notice of Compliance with Conditions (NOC/c) by Health Canada for the following indications: 1) as adjunctive treatment for the symptomatic relief of neuropathic pain in adult patients with multiple sclerosis; 2) as adjunctive analgesic treatment in adult patients with advanced cancer who experience moderate to severe pain during the highest tolerated dose of strong opioid therapy for persistent background pain [15].
Industrial hemp contains, by weight, far less CBD than CBD-rich cultivars such as Harlequin or Sour Tsunami. This means that producing a single 10 mL dose of CBD would require the cultivation and extraction of far more hemp than it would from whole-plant marijuana; thus raising the risk of exposing users to more contaminants. Hemp is classified as a “bioaccumulator,” or a plant that naturally absorbs toxicants from the soil.
Now 13, Jackson — whose diagnosis is undetermined — continues to use marijuana every day. (Like many patients, he ingests it in droplet form, which allows for more precise dosing and avoids lung problems.) He still has seizures, but they are less severe and they occur once every week or two, down from around 200 a month before he started using cannabis. He is back in school full time and is well enough to go on hikes and bike rides with his family.

The legality of smoked cannabis and oils differs by state, with some allowing only one or the other. Likewise, some states only approved the plant for use in a limited capacity, such as for children with epileptic disorders. It continues to be classified as a Schedule I drug, making it illegal under federal stipulations. When produced from industrial hemp products, cannabis oil may be legal, but when created from a crop of medical marijuana, its status reverts back to illegal unless the state has provisions for it.
As the benefits of CBD continue to become known, growers are modifying their crops to account for more cannabidiol and less tetrahydrocannabinol to create stronger medicinal plants. Some politicians believe that all plants with THC should be kept illegal, and as CBD plants become more commonly produced, doctors remind them that both compounds have certain benefits to be had by patients. The anti-nausea and appetite stimulating properties of THC make it an optimal treatment for some patients, depending upon their conditions and symptoms. Research also shows that the two compounds work best when together.
Both hemp and marijuana products are available in a variety of different forms, from oils and tinctures to edibles and chocolates. The main difference comes down to accessibility. Marijuana products are not legal in every state, and many states that do allow for medical marijuana require documentation or a card from your doctor. Usage also depends on what you want out of the product. You can’t use most forms of marijuana without getting high. Hemp products are mostly comprised of CBD with a fraction of a percent of THC (if any at all). This makes hemp oil more versatile for everyday use. Along with tinctures and oils, hemp is available in the form of capsules, edibles, chocolates, topical creams, lozenges, and more. Hemp oil is also great to cook with, and the wealth of products make measuring out and controlling serving sizes much easier. Hemp oil can also be used in vapes, but make sure you specifically get a hemp vape oil. A regular hemp oil or tincture, which is too thick to burn properly in a vape.
The base of so many great cannabis products starts with great cannabis oil. At Caliva, we invest in innovation and utilize cutting-edge oil extraction and refinement technology to to produce high purity cannabis oil. Our team of cultivators, scientists, and artisan formulators work together to produce the perfect oil blend to fit your product development needs. From vape cartridges, to specialty topicals, edibles and tincture, our oil formulations serve as the basis for high quality cannabis products. All Caliva oils are tested to 2018 California state standards. Our oil is sold by the kilo only and shipped in laboratory grade glass. 
Hemp oil — obtained by pressing benefit-rich hemp seeds — is slightly different than cannabis oil, although they both come from the same genus, Cannabis, and the same species, Cannabis Sativa. The term hemp is used to describe a Cannabis Sativa plant that contains only trace amounts of THC. Hemp is a high-growing plant that’s commonly grown for industrial uses, such as oils and topical ointments, as well as fiber for clothing, construction, paper and more.
AC/DC: A Sativa-dominant phenotype of Cannatonic, this cultivar boasts one of the highest ratios of CBD to THC, clocking in at 20:1. AC/DC is claimed to help reduce pain, anxiety, depression and migraines while reducing symptoms in patients with epilepsy, some forms of cancer, and multiple sclerosis. This cultivar’s pinene-rich terpene profile offers potent clear-headed pain relief.
"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia.
High-CBD strains tend to deliver very clear-headed, functional effects without the euphoric high associated with high-THC strains. They’re typically preferred by consumers who are extremely sensitive to the side effects of THC (e.g., anxiety, paranoia, dizziness). A high-CBD strain would also be a great choice for someone needing to medicate throughout the day to control pain, inflammation, anxiety, or other chronic conditions.
Choosing CBD products isn’t as simple as picking something off the dispensary shelf and then walking out the door. Consumers should be aware that a handful of hemp products on the market pay lip service to governmental regulations by labeling themselves as hemp, despite containing cannabinoids and terpenoids. Some CBD products are completely devoid of cannabinoids including CBD, despite package labeling. The FDA purchased a number of CBD products online in 2015 and 2016 to test them for the presence of CBD and other cannabinoids. They found that the amount of CBD these products claimed on their labels was markedly inaccurate; some didn’t even contain CBD.
I'm reading this in disbelief. I feel kind of numb to be honest. I'm in collection for thousands because of all the medical treatments, surgeries, and travel. For nearly 8 years my wife has worked two and sometimes 3 jobs and every time I was well enough I worked two jobs trying to catch up and still we fell behind. Call it pride or stupidity, but we never asked for help of any kind. I take care of older neighbors and spend much of my free time working with disabled veterans. I feel like I've given everything I had to help others my whole life. Thank You one and all!
Anxiety disorders are the most common mental health concern in the United States. An estimated 30 percent of adults in the United States (that's 66 million people) and an estimated 25 percent of teenagers and preteens are affected by anxiety. As a functional medicine practitioner, I see many people who struggle with anxiety and panic attacks, and from these statistics, it should be no surprise. But just because something is common doesn't make it normal. Fortunately, new insights into the cause of anxiety may help with the development of more effective treatment options.
Hemp and Marijuana come form the same plant family, but are completely different in function, cultivation and application. Marijuana generally has a high level of THC (a psychoactive compound that makes you feel “high”) and is used for medicinal or recreational purpose. Hemp contains a negligible amount of THC (but is high in CBD) and is used in dietary supplements, skin products, clothing and paper.
Both Bonn-Miller and Ward stress that it's up to the consumer to be well-educated about the material they're purchasing and the research that's out there. "The companies that are creating [cannabis oils] are offering lots of claims about its use that are not necessarily substantiated by any research," Bonn-Miller said. So "I think there needs to be, from a consumer standpoint, a lot of vigilance," he added.
Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, Moriello AS, Davis JB, Mechoulam R, Di Marzo V: Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br J Pharmacol. 2001 Oct;134(4):845-52. doi: 10.1038/sj.bjp.0704327. [PubMed:11606325]
REM behavior disorder: REM behavior disorder (RBD) is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep. For many, RBD is a symptom of a larger, more serious condition or disorder, such as Alzheimer’s disease or PTSD. CBD oil minimizes the symptoms of RBD, and also alleviates the anxiety and painful symptoms that often accompany disorders that lead to RBD.
Hemp Oil is processed from the seeds and stalks of the hemp plant and despite its source, it contains little to none of the psychoactive element Tetrahydrocannabinol (THC), meaning it cannot get you ‘high’. For instance hemp may contain 0.3-1.5% of THC whilst marijuana contains anything from 5% to 20% plus. Hemp oils main components are in fact omega fatty acids, similar to those which can be found in fish and olive oil.
The ACMPR requires that all Licensed Producers display total levels of potential THC and CBD on their product labels. Total potential THC is the total amount of THC available when all THCa (tetrahydrocannabinolic acid) is decarboxylated. Total potential CBD is the total of CBD available when all the CBDa (Cannabidiolic acid) is decarboxylated. Learn more about decarboxylation here.
CBD has some other very important jobs outside of the endocannabinoid system (ECS). For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A), which may explain CBD’s effects on depression and anxiety. It also acts at the peroxisome proliferator activated receptors (PPARs), which halt the proliferation of cancer cells and convey neuro- and cardioprotection. By interacting with a particular PPAR (gamma), CBD could prove to be a promising new way to prevent alzheimer’s disease and other brain disorders.
Historically, hemp could legally be grown and cultivated for academic research purposes only. However, the legality of hemp growth has changed in the past year. In April 2018, Sen. Mitch McConnell of Kentucky introduced the Hemp Farming Act of 2018, a piece of legislation that proposed legalizing all hemp products at the federal level. The act was incorporated in the 2018 United States Farm Bill, which passed in both the House and Senate in December 2018. Per the farm bill, industrial hemp will be descheduled as a federally controlled substance.
"Leah Bracknell, who played Zoe Tate in Emmerdale from 1989 until 2006, has been living with incurable lung cancer since discovering her illness two years ago. ...The former Emmerdale actress looked well as she smiled away to photographers. Leah appeared to share some hope with her fans on Instagram as she continues to battle cancer. “Someone’s watching over us." She continued: “So what does this mean? Quite simply it means hope." Leah also revealed she has been using homemade #cannabis oil as part of her treatment. “I decided to integrate plant medicine into my healing programme, and I began to use cannabis oil high in #THC medicinally from the day I left the hospital two years ago,” she wrote." https://www.express.co.uk/…/Leah-Bracknell-health-update-ca…
In 2015, researchers conducted a comprehensive review to get at the heart of CBD and its intervention of addictive behaviors. These researchers gathered 14 studies, nine (9) of which involved animals, while the remaining five (5) involved humans, to find that CBD may indeed have therapeutic properties on opioid, cocaine, and psychostimulant addiction. Further, studies heavily suggest that CBD may also be beneficial in the treatment of marijuana and tobacco addiction. One reason that CBD may be effective as treatment for addictive disorders is its ability to ease the anxiety that leads people to crave drugs like heroin.

CBD For Pain

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